Obese have right to 2 airline seats: Canada court

[rogueyam]

Here's one example from your precious article:

 

"Friedman and colleagues showed that leptin is a hormonal signal made by the bodyâ??s fat cells that regulates food intake and energy expenditure."

 

The author writes crap. Leptin might stimulate or repress appetite but food intake is a willful act by the eater. If someone decides to eat some fixed number of calories per day then they can and will do so. They might be more or less psychologically satisfied with this food intake level depending upon the hormones present in their system but those hormones do not regulate their behavior. They consciously choose their behavior.

 

Similarly with energy expenditure. Part of one'e energy expenditure is your basal metabolic rate, but exercise also requires energy expenditure. Hormone levels might influence the rate at which you burn calories while sitting still, but there is a fixed minimum caloric expenditure associated with any given physical exercise. As with food intake, the amount of exercise one performs is an act of will. Stay on the treadmill long enough and you will lose weight. Period.

 

The reason you are unable to analyze your precious little article like this, buttstick, is because you are stupid and ignorant. So you instead choose to spew inchoate hatred at me and verbally fellate your presumed scientist heroes. It is a pathetic display of the preening arrogance underlain by weakness and self-debasement that is typical of the leftist mind.

[rchapstick]

5555555555555!

 

RY, do you do 2 shows nightly? Hysterical stuff!

 

Yeah that Friedman guy and his noted leftist commie pinko socialist benefactor (David Rockefeller) are really pulling a fast one here. And of course, that lefty rag Nature is in cahoots with them.

 

The reason I am able to analyze this research (and not resort to infantile name-calling) is I actually got an education and am capable of critical thought. Apparently, your Associate of Arts degree from East Louisiana A&M Community College did not teach you how to think critically, has left you qualified only for the low-level pencil-pushing bureaucratic job that you now hold and will never rise above.

 

Enjoy your life of mediocrity, and keep on dreaming that you are intellectually superior to every else.

[rogueyam]

Yeah that Friedman guy and his noted leftist commie pinko socialist benefactor (David Rockefeller) are really pulling a fast one here. And of course, that lefty rag Nature is in cahoots with them.

 

If you had any sense you'd realize that I said nothing about Friedman one way or the other.

 

Rather I explained that the article is flawed and does not contradict my previous statement as you claimed.

 

If you're so smart, chapstick, then why are your posts so stupid?

 

You claim to have analyzed the article but your posts provide no such analysis. My posts, by contrast, do.

[Bangkoktraveler]

RY' date=' if you had bothered to read the article I linked earlier, you might realize what a crock of shit that statement is. [/quote']

 

I read the article. The difference between me and you is that I am intelligent and well-educated enough to recognize how incomplete the article is. You just see the credentials of the subject scientist and fall to your knees.

 

 

For a guy who flunked out of college, became a Democrat and voted for Clinton in 1992 and now hates gays, Mexicans and 'LEFTIST', you really have your act all together. Have you ever thoght about going back to Detroit?

[Bangkoktraveler]

Here's one example from your precious article:

 

"Friedman and colleagues showed that leptin is a hormonal signal made by the bodyâ??s fat cells that regulates food intake and energy expenditure."

 

The author writes crap. Leptin might stimulate or repress appetite but food intake is a willful act by the eater. If someone decides to eat some fixed number of calories per day then they can and will do so. They might be more or less psychologically satisfied with this food intake level depending upon the hormones present in their system but those hormones do not regulate their behavior. They consciously choose their behavior.

 

Similarly with energy expenditure. Part of one'e energy expenditure is your basal metabolic rate, but exercise also requires energy expenditure. Hormone levels might influence the rate at which you burn calories while sitting still, but there is a fixed minimum caloric expenditure associated with any given physical exercise. As with food intake, the amount of exercise one performs is an act of will. Stay on the treadmill long enough and you will lose weight. Period.

 

The reason you are unable to analyze your precious little article like this, buttstick, is because you are stupid and ignorant. So you instead choose to spew inchoate hatred at me and verbally fellate your presumed scientist heroes. [color:red]It is a pathetic display of the preening arrogance underlain by weakness and self-debasement that is typical of the leftist mind.[/color]

 

 

 

You should know what a 'leftist mind' is all about especially since you were a Democrat and voted for Clinton in 1992. How can you live with yourself? Does explain your anger.

[Bangkoktraveler]

5555555555555!

 

RY, do you do 2 shows nightly? Hysterical stuff!

 

Yeah that Friedman guy and his noted leftist commie pinko socialist benefactor (David Rockefeller) are really pulling a fast one here. And of course, that lefty rag Nature is in cahoots with them.

 

The reason I am able to analyze this research (and not resort to infantile name-calling) is I actually got an education and am capable of critical thought. Apparently, your Associate of Arts degree from East Louisiana A&M Community College did not teach you how to think critically, has left you qualified only for the low-level pencil-pushing bureaucratic job that you now hold and will never rise above.

 

Enjoy your life of mediocrity, and keep on dreaming that you are intellectually superior to every else.

 

 

Can you picture rogie taking a girl out on a date and then he starts spelling his normal putrid shit of 'Leftist', liar, etc.? Better yet can you

see why rogie does not go out on dates?

[rchapstick]

Yeah that Friedman guy and his noted leftist commie pinko socialist benefactor (David Rockefeller) are really pulling a fast one here. And of course' date=' that lefty rag Nature is in cahoots with them.[/quote']

 

If you had any sense you'd realize that I said nothing about Friedman one way or the other.

 

Rather I explained that the article is flawed and does not contradict my previous statement as you claimed.

 

If you're so smart, chapstick, then why are your posts so stupid?

 

You claim to have analyzed the article but your posts provide no such analysis. My posts, by contrast, do.

 

You did not explain that the article is flawed ... rather you simply stated it. Here is a a synposys from his on-line CV:

 

Dr. Friedmanâ??s lab identified leptin, a hormonal signal made by the bodyâ??s fat cells that regulates food intake and energy expenditure and has powerful effects on reproduction, metabolism, other endocrine systems and even immune function. Current research in the Friedman lab focuses on the genes and neural circuits that control food intake and body weight, and leptinâ??s mechanism of action and its relevance to the development of obesity.

 

In addition to its role in regulating weight, leptin is also involved in regulating many of the physiological responses that are seen with changes in nutritional state. Studies in Dr. Friedmanâ??s lab seek to elucidate the mechanism by which a single molecule, leptin, can modulate a complex behavior, feeding, and how leptin and other mechanisms control body weight and the pathogenesis of obesity. Dr. Friedman is also part of a collaboration to establish the genetic basis of human obesity on the Pacifi c island of Kosrae.

 

In December 1994, Dr. Friedman and his colleagues identified a gene in mice and humans called obese (ob) that codes for a hormone he later named leptin, after the Greek word leptos, for thin. Mice that lack ob, and thus do not produce leptin, are massively obese, weighing as much as three times more than their normal littermates. Dr. Friedman showed that after normal and ob mice are injected with synthetic leptin, they are more active and lose weight. In addition, humans lacking leptin eat copious amounts and are massively obese, and leptin treatment of these individuals leads to massive weight loss. The dramatic effect of leptin in these patients establishes a key role for this hormone in human physiology.

 

However, the majority of obese people have very high levels of leptin circulating in their blood. Dr. Friedmanâ??s lab went on to show that high leptin levels are associated with resistance to leptin and provided evidence that suggests that animals destined to be obese increase their production of leptin to satisfy a higher set point for weight. These observations have reframed views on the pathogenesis of obesity and suggested that the development of approaches to improve leptin response in resistant individuals could provide new treatments for obesity. In order to identify the molecular basis of leptin resistance, Dr. Friedman is also studying the neural circuit that is activated by leptin.

 

Leptin itself has proven to be an effective therapy for a number of other human conditions associated with low leptin levels, including several different forms of human diabetes and a condition known as hypothalamic amennorhea. This condition, which develops in extremely thin women â?? often ballet dancers or longdistance runners â?? is one of the most common causes of infertility in women, and leptin treatment has been shown to restore reproductive function in these patients. In addition, a subset of obese individuals also has relatively low leptin levels, and it appears that these individuals lose weight with leptin treatment. Dr. Friedman is now performing clinical studies at The Rockefeller University Hospital to determine the effects of leptin on the changes that occur in the body during signifi cant weight loss achieved by obese patients on a very low-calorie diet.

 

Dr. Friedman, with Jan Breslow and Markus Stoffel, also leads a team of Rockefeller researchers that is studying the genetic causes of a cluster of health problems called Syndrome X â?? obesity, diabetes, high blood pressure and high blood cholesterol â?? in a remote population of over 3,000 people on the Micronesian island Kosrae. By analyzing the genetic inheritance patterns of the entire Kosraean population, Dr. Friedman and his colleagues hope to solve the ongoing mystery of why some people develop these diseases while others with the same lifestyle do not.

 

CAREER

 

Dr. Friedman graduated from Rensselaer Polytechnic Institute magna cum laude and, in 1977 at the age of 22, received his M.D. from Albany Medical College of Union University. After completing two residencies at Albany Medical Center Hospital, Dr. Friedman came to Rockefeller as a postgraduate fellow and associate physician in 1980. In 1986, he received his Ph.D., working in the lab of James E. Darnell Jr., and was appointed assistant professor. In 1991 he was named head of laboratory, and in 1995 he was promoted to professor. He was appointed the Marilyn M. Simpson Professor in 1999. He has been an investigator at the Howard Hughes Medical Institute since 1986. Dr. Friedman also directs the Starr Center for Human Genetics, one of the countryâ??s largest centers for the study of diseases linked to heredity.

 

A member of the National Academy of Sciences and its Institute of Medicine, Dr. Friedmanâ??s most recent honors include the 2007 Jessie Stevenson Kovalenko Medal, the sixth Danone International Prize for Nutrition, the 2004 Gairdner Foundation International Award and the 2004 Passano Foundation Award.

 

 

 

If you'd like to further critique his work, I'd suggest you read his publications ... there are many. The Nature article, in particular, is excellent.

 

I met Friedman when he was a graduate student at Rockefeller, and he is profoundly brilliant. But putting that aside, who are we to believe? Friedman with his medical degree at age 22, a PhD, and the head of a laboratory in arguably the most prestigious medical research center in the country, or RY with his AA degree from East Buttfuck State, his cubicle office, his crap job, and his aggrandized feelings of intellectual superiority?

 

Geeeez, tough choice....

[Bangkoktraveler]

rogie didn't get his Associates degree. He fluked out. He does have his GED but it took him 3 whacks just to get that.

[rogueyam]

You did not explain that the article is flawed ... rather you simply stated it.

 

False. See my post at the top of this page.

 

 

...who are we to believe? Friedman...or RY

 

As I said before, I have posted not one word about Friedman or his work.

 

[rchapstick]

 

The author writes crap.

 

Sounds like you were critiquing his work to me ...

 

You are of the opinion that all people who are obese simply lack willpower. Friedman's research seems to rebuke that hypothesis pretty soundly.

 

The reality is RY that you are intellectually arrogant and lazy. If you are presented with a set of facts, or an opinion, that differs from your view of the world you invariably dismiss the hypothesis out of hand. People who are intellectually curious will look at the hypothesis with an open point of view, and try to determine if their own hypotheses need to be altered.

 

It is this attitude that prevents you from being successful in you career (well, that and the fact that you have the social skills of a slug).